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ac133 mutz 2 cells  (DSMZ)


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    Structured Review

    DSMZ ac133 mutz 2 cells
    Effects of exposure to increasing concentration of cordycepin on MUTZ−2 and primary AML cell viability. ( A ) Cell viability was analyzed through Trypan blue cell count in MUTZ−2 cells after cordycepin treatment at increasing concentrations (50, 100, 200 µM) for 24 and 48 h. ( B ) Dose- and time-response cytotoxicity of the drug were analyzed by the methyl thiazole tetrazolium (MTT) assay in MUTZ−2 cells treated with increasing concentrations of cordycepin (20, 50, 100 and 200 μM) for 24, 48 and 72 h. Values are expressed as the percentage of viable cells for each condition relative to controls. ( C ) MTT assay on mononuclear cells (MNCs) from an AML patient (AML#526) with increasing concentrations of cordycepin (50, 100 and 200 μM) for 24 h. ( D ) MTT assay on primary selected cells <t>(AC133</t> + ) from an AML patient (AML#523) with increasing concentrations of cordycepin (25, 50 and 100 μM) for 24 h. The relative IC 50 for MUTZ−2 is shown as the mean ± SD (standard deviation) of at least three independent experiments; the p -values are indicated in the graphs: * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001; ANOVA and Tukey’s multiple comparisons test.
    Ac133 Mutz 2 Cells, supplied by DSMZ, used in various techniques. Bioz Stars score: 91/100, based on 16 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ac133+mutz+2+cells/MUTZ-2/pmc10417454-36-0-4
    Average 91 stars, based on 16 article reviews
    ac133 mutz 2 cells - by Bioz Stars, 2026-10
    91/100 stars

    Images

    1) Product Images from "Cordycepin (3′dA) Induces Cell Death of AC133 + Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC"

    Article Title: Cordycepin (3′dA) Induces Cell Death of AC133 + Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC

    Journal: Cancers

    doi: 10.3390/cancers15153931

    Effects of exposure to increasing concentration of cordycepin on MUTZ−2 and primary AML cell viability. ( A ) Cell viability was analyzed through Trypan blue cell count in MUTZ−2 cells after cordycepin treatment at increasing concentrations (50, 100, 200 µM) for 24 and 48 h. ( B ) Dose- and time-response cytotoxicity of the drug were analyzed by the methyl thiazole tetrazolium (MTT) assay in MUTZ−2 cells treated with increasing concentrations of cordycepin (20, 50, 100 and 200 μM) for 24, 48 and 72 h. Values are expressed as the percentage of viable cells for each condition relative to controls. ( C ) MTT assay on mononuclear cells (MNCs) from an AML patient (AML#526) with increasing concentrations of cordycepin (50, 100 and 200 μM) for 24 h. ( D ) MTT assay on primary selected cells (AC133 + ) from an AML patient (AML#523) with increasing concentrations of cordycepin (25, 50 and 100 μM) for 24 h. The relative IC 50 for MUTZ−2 is shown as the mean ± SD (standard deviation) of at least three independent experiments; the p -values are indicated in the graphs: * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001; ANOVA and Tukey’s multiple comparisons test.
    Figure Legend Snippet: Effects of exposure to increasing concentration of cordycepin on MUTZ−2 and primary AML cell viability. ( A ) Cell viability was analyzed through Trypan blue cell count in MUTZ−2 cells after cordycepin treatment at increasing concentrations (50, 100, 200 µM) for 24 and 48 h. ( B ) Dose- and time-response cytotoxicity of the drug were analyzed by the methyl thiazole tetrazolium (MTT) assay in MUTZ−2 cells treated with increasing concentrations of cordycepin (20, 50, 100 and 200 μM) for 24, 48 and 72 h. Values are expressed as the percentage of viable cells for each condition relative to controls. ( C ) MTT assay on mononuclear cells (MNCs) from an AML patient (AML#526) with increasing concentrations of cordycepin (50, 100 and 200 μM) for 24 h. ( D ) MTT assay on primary selected cells (AC133 + ) from an AML patient (AML#523) with increasing concentrations of cordycepin (25, 50 and 100 μM) for 24 h. The relative IC 50 for MUTZ−2 is shown as the mean ± SD (standard deviation) of at least three independent experiments; the p -values are indicated in the graphs: * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001; ANOVA and Tukey’s multiple comparisons test.

    Techniques Used: Concentration Assay, Cell Counting, MTT Assay, Standard Deviation

    Related Articles

    Concentration Assay:

    Article Title: Cordycepin (3′dA) Induces Cell Death of AC133 + Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC
    Article Snippet: AC133 + -MUTZ-2 cells (DSMZ ACC 271) were grown in 60% alpha-MEM (Gibco) medium, complemented with 20% fetal bovine serum (FBS), 20% vol conditioned medium by 5637 cell line (DSM ACC 35), 1% penicillin/streptomycin, 1% of glutamine and 50 ng/mL SCF (STEM CELL Technologies).

    Article Title: Cordycepin (3'dA) Induces Cell Death of AC133 + Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC .
    Article Snippet: AC133+-MUTZ-2 cells (DSMZ ACC 271) were grown in 60% alpha-MEM (Gibco) medium, complemented with 20% fetal bovine serum (FBS), 20% vol conditioned medium by 5637 cell line (DSM ACC 35), 1% penicillin/streptomycin, 1% of glutamine and 50 ng/mL SCF (STEM CELL Technologies).

    Cell Counting:

    Article Title: Cordycepin (3′dA) Induces Cell Death of AC133 + Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC
    Article Snippet: AC133 + -MUTZ-2 cells (DSMZ ACC 271) were grown in 60% alpha-MEM (Gibco) medium, complemented with 20% fetal bovine serum (FBS), 20% vol conditioned medium by 5637 cell line (DSM ACC 35), 1% penicillin/streptomycin, 1% of glutamine and 50 ng/mL SCF (STEM CELL Technologies).

    Article Title: Cordycepin (3'dA) Induces Cell Death of AC133 + Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC .
    Article Snippet: AC133+-MUTZ-2 cells (DSMZ ACC 271) were grown in 60% alpha-MEM (Gibco) medium, complemented with 20% fetal bovine serum (FBS), 20% vol conditioned medium by 5637 cell line (DSM ACC 35), 1% penicillin/streptomycin, 1% of glutamine and 50 ng/mL SCF (STEM CELL Technologies).

    MTT Assay:

    Article Title: Cordycepin (3′dA) Induces Cell Death of AC133 + Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC
    Article Snippet: AC133 + -MUTZ-2 cells (DSMZ ACC 271) were grown in 60% alpha-MEM (Gibco) medium, complemented with 20% fetal bovine serum (FBS), 20% vol conditioned medium by 5637 cell line (DSM ACC 35), 1% penicillin/streptomycin, 1% of glutamine and 50 ng/mL SCF (STEM CELL Technologies).

    Article Title: Cordycepin (3'dA) Induces Cell Death of AC133 + Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC .
    Article Snippet: AC133+-MUTZ-2 cells (DSMZ ACC 271) were grown in 60% alpha-MEM (Gibco) medium, complemented with 20% fetal bovine serum (FBS), 20% vol conditioned medium by 5637 cell line (DSM ACC 35), 1% penicillin/streptomycin, 1% of glutamine and 50 ng/mL SCF (STEM CELL Technologies).

    Standard Deviation:

    Article Title: Cordycepin (3′dA) Induces Cell Death of AC133 + Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC
    Article Snippet: AC133 + -MUTZ-2 cells (DSMZ ACC 271) were grown in 60% alpha-MEM (Gibco) medium, complemented with 20% fetal bovine serum (FBS), 20% vol conditioned medium by 5637 cell line (DSM ACC 35), 1% penicillin/streptomycin, 1% of glutamine and 50 ng/mL SCF (STEM CELL Technologies).

    Article Title: Cordycepin (3'dA) Induces Cell Death of AC133 + Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC .
    Article Snippet: AC133+-MUTZ-2 cells (DSMZ ACC 271) were grown in 60% alpha-MEM (Gibco) medium, complemented with 20% fetal bovine serum (FBS), 20% vol conditioned medium by 5637 cell line (DSM ACC 35), 1% penicillin/streptomycin, 1% of glutamine and 50 ng/mL SCF (STEM CELL Technologies).



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    DSMZ ac133 mutz 2 cells
    Effects of exposure to increasing concentration of cordycepin on MUTZ−2 and primary AML cell viability. ( A ) Cell viability was analyzed through Trypan blue cell count in MUTZ−2 cells after cordycepin treatment at increasing concentrations (50, 100, 200 µM) for 24 and 48 h. ( B ) Dose- and time-response cytotoxicity of the drug were analyzed by the methyl thiazole tetrazolium (MTT) assay in MUTZ−2 cells treated with increasing concentrations of cordycepin (20, 50, 100 and 200 μM) for 24, 48 and 72 h. Values are expressed as the percentage of viable cells for each condition relative to controls. ( C ) MTT assay on mononuclear cells (MNCs) from an AML patient (AML#526) with increasing concentrations of cordycepin (50, 100 and 200 μM) for 24 h. ( D ) MTT assay on primary selected cells <t>(AC133</t> + ) from an AML patient (AML#523) with increasing concentrations of cordycepin (25, 50 and 100 μM) for 24 h. The relative IC 50 for MUTZ−2 is shown as the mean ± SD (standard deviation) of at least three independent experiments; the p -values are indicated in the graphs: * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001; ANOVA and Tukey’s multiple comparisons test.
    Ac133 Mutz 2 Cells, supplied by DSMZ, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ac133+mutz+2+cells/MUTZ-2/pmc10417454-36-0-4
    Average 91 stars, based on 1 article reviews
    ac133 mutz 2 cells - by Bioz Stars, 2026-10
    91/100 stars
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    Effects of exposure to increasing concentration of cordycepin on MUTZ−2 and primary AML cell viability. ( A ) Cell viability was analyzed through Trypan blue cell count in MUTZ−2 cells after cordycepin treatment at increasing concentrations (50, 100, 200 µM) for 24 and 48 h. ( B ) Dose- and time-response cytotoxicity of the drug were analyzed by the methyl thiazole tetrazolium (MTT) assay in MUTZ−2 cells treated with increasing concentrations of cordycepin (20, 50, 100 and 200 μM) for 24, 48 and 72 h. Values are expressed as the percentage of viable cells for each condition relative to controls. ( C ) MTT assay on mononuclear cells (MNCs) from an AML patient (AML#526) with increasing concentrations of cordycepin (50, 100 and 200 μM) for 24 h. ( D ) MTT assay on primary selected cells (AC133 + ) from an AML patient (AML#523) with increasing concentrations of cordycepin (25, 50 and 100 μM) for 24 h. The relative IC 50 for MUTZ−2 is shown as the mean ± SD (standard deviation) of at least three independent experiments; the p -values are indicated in the graphs: * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001; ANOVA and Tukey’s multiple comparisons test.

    Journal: Cancers

    Article Title: Cordycepin (3′dA) Induces Cell Death of AC133 + Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC

    doi: 10.3390/cancers15153931

    Figure Lengend Snippet: Effects of exposure to increasing concentration of cordycepin on MUTZ−2 and primary AML cell viability. ( A ) Cell viability was analyzed through Trypan blue cell count in MUTZ−2 cells after cordycepin treatment at increasing concentrations (50, 100, 200 µM) for 24 and 48 h. ( B ) Dose- and time-response cytotoxicity of the drug were analyzed by the methyl thiazole tetrazolium (MTT) assay in MUTZ−2 cells treated with increasing concentrations of cordycepin (20, 50, 100 and 200 μM) for 24, 48 and 72 h. Values are expressed as the percentage of viable cells for each condition relative to controls. ( C ) MTT assay on mononuclear cells (MNCs) from an AML patient (AML#526) with increasing concentrations of cordycepin (50, 100 and 200 μM) for 24 h. ( D ) MTT assay on primary selected cells (AC133 + ) from an AML patient (AML#523) with increasing concentrations of cordycepin (25, 50 and 100 μM) for 24 h. The relative IC 50 for MUTZ−2 is shown as the mean ± SD (standard deviation) of at least three independent experiments; the p -values are indicated in the graphs: * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001; ANOVA and Tukey’s multiple comparisons test.

    Article Snippet: AC133 + -MUTZ-2 cells (DSMZ ACC 271) were grown in 60% alpha-MEM (Gibco) medium, complemented with 20% fetal bovine serum (FBS), 20% vol conditioned medium by 5637 cell line (DSM ACC 35), 1% penicillin/streptomycin, 1% of glutamine and 50 ng/mL SCF (STEM CELL Technologies).

    Techniques: Concentration Assay, Cell Counting, MTT Assay, Standard Deviation